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1

Insulinoma Localization by Glucagon-Like Peptide-1 Receptor Imaging After 18 Years of Hypoglycemia

Kyrilli, Aglaia, Igoillo-Esteve, Mariana, Féry, Françoise, Grieco, Fabio A., Eisendrath, Pierre, Blocklet, Didier, Goldman, Serge, Henquin, Jean-Claude, Gotthardt, Martin, Cnop, Miriam

Journal:

AACE Clinical Case Reports

Year:

2015

Language:

english

File:

PDF, 1.53 MB

english, 2015

2

DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients

Volkmar, Michael, Dedeurwaerder, Sarah, Cunha, Daniel A, Ndlovu, Matladi N, Defrance, Matthieu, Deplus, Rachel, Calonne, Emilie, Volkmar, Ute, Igoillo-Esteve, Mariana, Naamane, Najib, Del Guerra, Silv

Journal:

The EMBO Journal

Year:

2012

Language:

english

File:

PDF, 2.68 MB

english, 2012

3

The long lifespan and low turnover of human islet beta cells estimated by mathematical modelling of lipofuscin accumulation

M. Cnop, S. J. Hughes, M. Igoillo-Esteve, M. B. Hoppa, F. Sayyed, L. van de Laar, J. H. Gunter, E. J. P. de Koning, G. V. Walls, D. W. G. Gray, P. R. V. Johnson, B. C. Hansen, J. F. Morris, M. Pipelee

Journal:

Year:

2010

Language:

english

File:

PDF, 403 KB

english, 2010

4

Palmitate induces a pro-inflammatory response in human pancreatic islets that mimicsCCL2expression by beta cells in type 2 diabetes

M. Igoillo-Esteve, L. Marselli, D. A. Cunha, L. Ladrière, F. Ortis, F. A. Grieco, F. Dotta, G. C. Weir, P. Marchetti, D. L. Eizirik, M. Cnop

Journal:

Year:

2010

Language:

english

File:

PDF, 1.64 MB

english, 2010

5

Erratum to: Palmitate induces a pro-inflammatory response in human pancreatic islets that mimicsCCL2expression by beta cells in type 2 diabetes

M. Igoillo-Esteve, L. Marselli, D. A. Cunha, L. Ladrière, F. Ortis, F. A. Grieco, F. Dotta, G. C. Weir, P. Marchetti, D. L. Eizirik, M. Cnop

Journal:

Year:

2012

Language:

english

File:

PDF, 65 KB

english, 2012

6

Causes and cures for endoplasmic reticulum stress in lipotoxic β-cell dysfunction

M. Cnop, L. Ladrière, M. Igoillo-Esteve, R. F. Moura, D. A. Cunha

Journal:

Diabetes, Obesity and Metabolism

Year:

2010

Language:

english

File:

PDF, 579 KB

english, 2010

7

Longevity of human islet α- and β-cells

M. Cnop, M. Igoillo-Esteve, S. J. Hughes, J. N. Walker, I. Cnop, A. Clark

Journal:

Diabetes, Obesity and Metabolism

Year:

2011

Language:

english

File:

PDF, 883 KB

english, 2011

8

Glycosomal ABC transporters of Trypanosoma brucei: Characterisation of their expression, topology and substrate specificity

Mariana Igoillo-Esteve, Muriel Mazet, Gladys Deumer, Pierre Wallemacq, Paul A.M. Michels

Journal:

International Journal for Parasitology

Year:

2011

Language:

english

File:

PDF, 734 KB

english, 2011

9

The glucose-6-phosphate dehydrogenase from Trypanosoma cruzi: Its role in the defense of the parasite against oxidative stress

Mariana Igoillo-Esteve, Juan José Cazzulo

Journal:

Molecular and Biochemical Parasitology

Year:

2006

Language:

english

File:

PDF, 419 KB

english, 2006

10

Death Protein 5 and p53-Upregulated Modulator of Apoptosis Mediate the Endoplasmic Reticulum Stress-Mitochondrial Dialog Triggering Lipotoxic Rodent and Human -Cell Apoptosis

Cunha, D. A., Igoillo-Esteve, M., Gurzov, E. N., Germano, C. M., Naamane, N., Marhfour, I., Fukaya, M., Vanderwinden, J.-M., Gysemans, C., Mathieu, C., Marselli, L., Marchetti, P., Harding, H. P., Ron

Journal:

Year:

2012

Language:

english

File:

PDF, 1.91 MB

english, 2012

11

Central role and mechanisms of β-cell dysfunction and death in friedreich ataxia-associated diabetes

Cnop, Miriam, Igoillo-Esteve, Mariana, Rai, Myriam, Begu, Audrey, Serroukh, Yasmina, Depondt, Chantal, Musuaya, Anyishai E., Marhfour, Ihsane, Ladrière, Laurence, Moles Lopez, Xavier, Lefkaditis, Dion

Journal:

Annals of Neurology

Year:

2012

Language:

english

File:

PDF, 495 KB

english, 2012

12

The Human Pancreatic Islet Transcriptome: Expression of Candidate Genes for Type 1 Diabetes and the Impact of Pro-Inflammatory Cytokines

Eizirik, Décio L., Sammeth, Michael, Bouckenooghe, Thomas, Bottu, Guy, Sisino, Giorgia, Igoillo-Esteve, Mariana, Ortis, Fernanda, Santin, Izortze, Colli, Maikel L., Barthson, Jenny, Bouwens, Luc, Hugh

Journal:

Year:

2012

Language:

english

File:

PDF, 1018 KB

english, 2012

13

The 6-Phosphogluconate Dehydrogenase of Leishmania (Leishmania) mexicana: Gene Characterization and Protein Structure Prediction

González, Deyanira, Pérez, José Luis, Serrano, María Luisa, Igoillo-Esteve, Mariana, Cazzulo, Juan José, Barrett, Michael P., Bubis, José, Mendoza-León, Alexis

Journal:

Journal of Molecular Microbiology and Biotechnology

Year:

2010

Language:

english

File:

PDF, 974 KB

english, 2010

14

RNA Sequencing Identifies Dysregulation of the Human Pancreatic Islet Transcriptome by the Saturated Fatty Acid Palmitate

Cnop, M., Abdulkarim, B., Bottu, G., Cunha, D. A., Igoillo-Esteve, M., Masini, M., Turatsinze, J.-V., Griebel, T., Villate, O., Santin, I., Bugliani, M., Ladriere, L., Marselli, L., McCarthy, M. I., M

Journal:

Year:

2014

Language:

english

File:

PDF, 5.62 MB

english, 2014

15

Diabetes in Friedreich Ataxia

Cnop, Miriam, Mulder, Hindrik, Igoillo-Esteve, Mariana

Journal:

Journal of Neurochemistry

Year:

2013

Language:

english

File:

PDF, 391 KB

english, 2013

16

Unveiling a common mechanism of apoptosis in -cells and neurons in Friedreich's ataxia

Igoillo-Esteve, M., Gurgul-Convey, E., Hu, A., Romagueira Bichara Dos Santos, L., Abdulkarim, B., Chintawar, S., Marselli, L., Marchetti, P., Jonas, J.-C., Eizirik, D. L., Pandolfo, M., Cnop, M.

Journal:

Human Molecular Genetics

Year:

2015

Language:

english

File:

PDF, 684 KB

english, 2015

17

Pancreatic β-cells activate a JunB/ATF3-dependent survival pathway during inflammation

Gurzov, E N, Barthson, J, Marhfour, I, Ortis, F, Naamane, N, Igoillo-Esteve, M, Gysemans, C, Mathieu, C, Kitajima, S, Marchetti, P, Ørntoft, T F, Bakiri, L, Wagner, E F, Eizirik, D L

Journal:

Year:

2012

Language:

english

File:

PDF, 715 KB

english, 2012

18

STAT1 Is a Master Regulator of Pancreatic -Cell Apoptosis and Islet Inflammation

Moore, F., Naamane, N., Colli, M. L., Bouckenooghe, T., Ortis, F., Gurzov, E. N., Igoillo-Esteve, M., Mathieu, C., Bontempi, G., Thykjaer, T., Orntoft, T. F., Eizirik, D. L.

Journal:

Journal of Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 5.56 MB

english, 2011

19

Glucagon-Like Peptide-1 Agonists Protect Pancreatic -Cells From Lipotoxic Endoplasmic Reticulum Stress Through Upregulation of BiP and JunB

Cunha, D. A., Ladriere, L., Ortis, F., Igoillo-Esteve, M., Gurzov, E. N., Lupi, R., Marchetti, P., Eizirik, D. L., Cnop, M.

Journal:

Year:

2009

Language:

english

File:

PDF, 419 KB

english, 2009

20

Enhanced Signaling Downstream of Ribonucleic Acid-Activated Protein Kinase-Like Endoplasmic Reticulum Kinase Potentiates Lipotoxic Endoplasmic Reticulum Stress in Human Islets

Ladrière, Laurence, Igoillo-Esteve, Mariana, Cunha, Daniel A., Brion, Jean-Pierre, Bugliani, Marco, Marchetti, Piero, Eizirik, Décio L., Cnop, Miriam

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2010

Language:

english

File:

PDF, 449 KB

english, 2010

21

tRNA Methyltransferase Homolog Gene TRMT10A Mutation in Young Onset Diabetes and Primary Microcephaly in Humans

Igoillo-Esteve, Mariana, Genin, Anne, Lambert, Nelle, DÃ©sir, Julie, Pirson, Isabelle, Abdulkarim, Baroj, Simonis, Nicolas, Drielsma, Anais, Marselli, Lorella, Marchetti, Piero, Vanderhaeghen, Pierre,

Journal:

Year:

2013

Language:

english

File:

PDF, 8.74 MB

english, 2013

22

A missense mutation in PPP1R15B causes a syndrome including diabetes, short stature and microcephaly

Abdulkarim, Baroj, Nicolino, Marc, Igoillo-Esteve, Mariana, Daures, Mathilde, Romero, Sophie, Philippi, Anne, Senée, Valérie, Lopes, Miguel, Cunha, Daniel A., Harding, Heather P., Derbois, Céline, Ben

Journal:

Year:

2015

Language:

english

File:

PDF, 3.70 MB

english, 2015

23

Cytokines induce endoplasmic reticulum stress in human, rat and mouse beta cells via different mechanisms

Brozzi, Flora, Nardelli, Tarlliza R., Lopes, Miguel, Millard, Isabelle, Barthson, Jenny, Igoillo-Esteve, Mariana, Grieco, Fabio A., Villate, Olatz, Oliveira, Joana M., Casimir, Marina, Bugliani, Marco

Journal:

Year:

2015

Language:

english

File:

PDF, 629 KB

english, 2015

24

The Transcription Factor B-Cell Lymphoma (BCL)-6 Modulates Pancreatic β-Cell Inflammatory Responses

Igoillo-Esteve, Mariana, Gurzov, Esteban N., Eizirik, Décio L., Cnop, Miriam

Journal:

Year:

2011

File:

PDF, 1.46 MB

2011

25

The Transcription Factor B-Cell Lymphoma (BCL)-6 Modulates Pancreatic β-Cell Inflammatory Responses

Igoillo-Esteve, Mariana, Gurzov, Esteban N., Eizirik, Décio L., Cnop, Miriam

Journal:

Year:

2011

Language:

english

File:

PDF, 1.46 MB

english, 2011

26

CO-51: La déficience de TRMT10A, une méthyltransférase d'ARNt, active la voie intrinsèque de l'apoptose dans les cellules bêta-pancréatiques

Igoillo-Esteve, M., Cosentino, C., Oltean, T., Atta, M., Ravanat, J., Eizirik, D., Cnop, M.

Journal:

Diabetes & Metabolism

Year:

2016

Language:

french

File:

PDF, 80 KB

french, 2016

27

CAD-17: Le transcriptome rencontre le protéome : un aperçu des médiateurs de lipotoxicité dans les cellules β-pancréatiques

Ghaddar, K., Lytrivi, M., Lopes, M., Igoillo-Esteve, M., Cunha, D.A., Marchetti, P., Eizirik, D.L., Ortsäter, H., Cnop, M.

Journal:

Diabetes & Metabolism

Year:

2016

Language:

french

File:

PDF, 50 KB

french, 2016

28

An update on lipotoxic endoplasmic reticulum stress in pancreatic β-cells

Cnop, Miriam, Igoillo-Esteve, Mariana, Cunha, Daniel A., Ladrière, Laurence, Eizirik, Décio L.

Journal:

Biochemical Society Transactions

Year:

2008

Language:

english

File:

PDF, 440 KB

english, 2008

29

Elucidation des mécanismes pathogènes du diabète induit par une déficience en TRMT10A et identification des nouvelles approches thérapeutiques

Igoillo-Esteve, Mariana, Cosentino, Cristina, Atta, Mohamed, Ravanat, Jean-Luc, L Eizirik, Decio, Cnop, Miriam

Journal:

Diabetes & Metabolism

Year:

2017

Language:

french

File:

PDF, 66 KB

french, 2017

30

Endoplasmic reticulum stress and eIF2α phosphorylation: The Achilles heel of pancreatic β cells

Cnop, Miriam, Toivonen, Sanna, Igoillo-Esteve, Mariana, Salpea, Paraskevi

Journal:

Molecular Metabolism

Year:

2017

Language:

english

File:

PDF, 2.34 MB

english, 2017

31

JNK Activation of BIM Promotes Hepatic Oxidative Stress, Steatosis and Insulin Resistance in Obesity

Litwak, Sara A., Pang, Lokman, Galic, Sandra, Igoillo-Esteve, Mariana, Stanley, William J., Turatsinze, Jean-Valery, Loh, Kim, Thomas, Helen E., Sharma, Arpeeta, Trepo, Eric, Moreno, Christophe, Gough

Journal:

Year:

2017

Language:

english

File:

PDF, 9.18 MB

english, 2017

32

Glucose-6-Phosphate Dehydrogenase of Trypanosomatids: Characterization, Target Validation, and Drug Discovery

Gupta, Shreedhara, Igoillo-Esteve, Mariana, Michels, Paul A. M., Cordeiro, Artur T.

Journal:

Molecular Biology International

Year:

2011

Language:

english

File:

PDF, 2.74 MB

english, 2011

33

The pentose phosphate pathway in Trypanosoma cruzi: a potential target for the chemotherapy of Chagas disease

Igoillo-Esteve, Mariana, Maugeri, Dante, Stern, Ana L., Beluardi, Paula, Cazzulo, Juan J.

Journal:

Anais da Academia Brasileira de Ciências

Year:

2007

Language:

english

File:

PDF, 1.49 MB

english, 2007

34

Inflammatory stress in islet β-cells: therapeutic implications for type 2 diabetes?

Lytrivi, Maria, Igoillo-Esteve, Mariana, Cnop, Miriam

Journal:

Current Opinion in Pharmacology

Year:

2018

File:

PDF, 557 KB

2018

35

Inflammatory stress in islet β-cells: therapeutic implications for type 2 diabetes?

Lytrivi, Maria, Igoillo-Esteve, Mariana, Cnop, Miriam

Journal:

Current Opinion in Pharmacology

Year:

2018

Language:

english

File:

PDF, 557 KB

english, 2018

36

In vitro use of free fatty acids bound to albumin: A comparison of protocols

Oliveira, Ana F, Cunha, Daniel A, Ladriere, Laurence, Igoillo-Esteve, Mariana, Bugliani, Marco, Marchetti, Piero, Cnop, Miriam

Journal:

Year:

2015

Language:

english

File:

PDF, 492 KB

english, 2015

37

The tRNA Epitranscriptome and Diabetes: Emergence of tRNA Hypomodifications as a Cause of Pancreatic β-Cell Failure

Cosentino, Cristina, Cnop, Miriam, Igoillo-Esteve, Mariana

Journal:

Year:

2019

Language:

english

File:

PDF, 1.06 MB

english, 2019

38

Enhanced Signaling Downstream of Ribonucleic Acid-Dependent Protein Kinase-Like Kinase Potentiates Lipotoxic Endoplasmic Reticulum Stress in Human Islets

Ladriere, Laurence, Igoillo-Esteve, Mariana, Cunha, Daniel A., Brion, Jean-Pierre, Bugliani, Marco, Marchetti, Piero, Eizirik, DeÌcio L., Cnop, Miriam

Journal:

Molecular Endocrinology

Year:

2010

File:

PDF, 74 KB

2010

39

Combined transcriptome and proteome profiling of the pancreatic Î²-cell response to palmitate unveils key pathways of Î²-cell lipotoxicity

Lytrivi, Maria, Ghaddar, Kassem, Lopes, Miguel, Rosengren, Victoria, Piron, Anthony, Yi, Xiaoyan, Johansson, Henrik, LehtiÃ¶, Janne, Igoillo-Esteve, Mariana, Cunha, Daniel A., Marselli, Lorella, March

Journal:

Year:

2020

File:

PDF, 1.44 MB

2020